Fen Wang, M.D.
Associate chief physician, Department of Neurology
SUMMARY
Dr. Fen Wang, associate chief physician in Department of Neurology of Xuanwu Hospital. She received her M.D. degree in Neurology from Capital Medical University in 2007, and has served on the faculty of Xuanwu Hospital for 9 years.
Dr. Wang’s research focuses on identifying the genetic variations associated with Alzheimer’s disease, and evaluating of genetic and non-genetic risk factors, and exploring the strategies of early identification and prevention the onset of Alzheimer's disease.
Three representative publications:
1.    Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman JM, Graff-Radford NR, Ghetti B, Farlow MR, Sperling R, Salloway S, Schofield PR, Masters CL, Martins RN, Rossor MN, Jucker M, Danek A, Förster S, Lane CA, Morris JC, Benzinger TL, Bateman RJ; Dominantly Inherited Alzheimer Network; Dominantly Inherited Alzheimer Network. Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology. 2015;85(9):790-798.
2.    Wang F, Shu C, Jia L, Zuo X, Zhang Y, Zhou A, Qin W, Song H, Wei C, Zhang F, Hong Z, Tang M, Wang D, Jia J. Exploration of 16 candidate genes identifies the association of IDE with Alzheimer’s disease in Han Chinese. Neurobiol Aging. 2012; (33): 1014.e1-1014.e9.
3.    Wang F, Jia J. Polymorphisms of cholesterol metabolism genes CYP46 and ABCA1 and the risk of sporadic Alzheimer's disease in Chinese. Brain Res. 2007;1147:34-38.
RESEARCH INTERESTS
1. Genetic studies for Alzheimer's disease
The aim of this direction is to screen and identify the genetic variations associated with Alzheimer’s disease, and explore the pathological basis between them.
2. Longitudinal clinical studies for Alzheimer's disease
The aim of this direction is to find predictors of cognitive decline and establish strategies to prevent or delay the onset of Alzheimer's disease through longitudinal cohorts.
AWARDS AND HONORS
2013    State Scientific and Technological Progress Award (2nd Class)
    As the Ninth Contributor
2010     Beijing Science and Technology Progress Award (2nd Class)
    As the Fifth Contributor
2009    Chinese Medical Science and Technology Prize (2nd Class)
    As the Third Contributor
PUBLICATIONS
1.    Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman JM, Graff-Radford NR, Ghetti B, Farlow MR, Sperling R, Salloway S, Schofield PR, Masters CL, Martins RN, Rossor MN, Jucker M, Danek A, Förster S, Lane CA, Morris JC, Benzinger TL, Bateman RJ; Dominantly Inherited Alzheimer Network; Dominantly Inherited Alzheimer Network. Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology. 2015;85(9):790-798.
2.    Jia J, Zhou A, Wei C, Jia X, Wang F, Li F, Wu X, Mok V, Gauthier S, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X. The prevalence of mild cognitive impairment and its etiological subtypes in elderly Chinese. Alzheimers Dement. 2014 Jan 10. pii: S1552-5260(13)02843-4. doi: 10.1016/j.jalz.2013.09.008.
3.    Jia J, Wang F, Wei C, Zhou A, Jia X, Li F, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X. The prevalence of dementia in urban and rural areas of China. Alzheimers Dement. 2014 Jan; 10(1):1-9.
4.    Xu M, Da YW, Liu L, Wang F, Jia JP. Giant axonal neuropathy caused by a novel compound heterozygous mutation in the gigaxonin gene. J Child Neurol. 2013 Oct;28(10):1316-1319.
5.    Li F, Wang F, Jia J. Evaluating the prevalence of dementia in hospitalized older adults and effects of comorbid dementia on patients' hospital course. Aging Clin Exp Res 2013;25(4):393-401.